Attended Methodist Primary School in Kano where he obtained First School Leaving Certificate, proceeded to the prestigious St Thomas Senior Secondary School in Kano where he had his SSCE meritoriously, Daniel U.S. Onyetulem holds an MBBS degree from the prestigious Ahmadu Bello University Zaria. Obtained a degree in Occupational Health and Safety Management from the British Safety Council as well as a Diploma in Occupational Medicine in The United Kingdom.

The MPH program at the Federal University of Technology Owerri where he has completed his coursework, Certificate in Economic Evaluation in Global Health (EEGH), Leadership & Management in Health (LMIH), and Global Health Project Management (GHPM) all from the University of Washington. Obtained an MBA from Enugu State University of Technology Business School and several certificate programs from Johns Hopkins University, United States of America.